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PKP2


Official Full Name
plakophilin 2
Organism
Homo sapiens
Gene ID
5318
Background
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene may regulate the signaling activity of beta-catenin and is required to maintain transcription of genes that control intracellular calcium cycling including ryanodine receptor 2, ankyrin-B, triadin, and calcium channel, voltage-dependent, L type, alpha 1C. Mutations in this gene are associated with different inherited cardiac conditions including Arrythmogenic Cardiomyopathy, Brugada Syndrome, and Idiopathic Ventricular Fibrillation. A processed pseudogene with high similarity to this gene has been mapped to chromosome 12p13. [provided by RefSeq, May 2022]
Synonyms
ARVD9

Cat.No. Product Name Price
SHH376612 shRNA set against Mouse PKP2 (NM_026163.2) Inquiry
SHH376616 shRNA set against Rat PKP2 (NM_001100499.1) Inquiry
SHR118344 shRNA set against Human PKP2(NM_004572.3) Inquiry
SHR118380 shRNA set against Human PKP2(NM_001005242.2) Inquiry
SHR118398 shRNA set against Mouse Pkp2(NM_026163.2) Inquiry
SHW012173 shRNA set against Danio rerio PKP2 (NM_001113433) Inquiry
Cat.No. Product Name Price
CDCR258261 Mouse Pkp2 ORF Clone(NM_026163.2) Inquiry
CDFR005250 Rat Pkp2 cDNA Clone(NM_001100499.1) Inquiry
MiUTR1H-07948 PKP2 miRNA 3'UTR clone Inquiry
MiUTR1H-07949 PKP2 miRNA 3'UTR clone Inquiry
MiUTR1M-09275 PKP2 miRNA 3'UTR clone Inquiry
CDCB157936 Human PKP2 ORF clone (BC126199) Inquiry
CDCB173648 Danio rerio PKP2 ORF Clone (NM_001113433) Inquiry
CDCB189176 Rabbit PKP2 ORF clone (XM_008259408.1) Inquiry
CDCH064372 human PKP2 ORF clone (NM_001005242.2) Inquiry
CDCR372291 Rat Pkp2 ORF Clone(NM_001100499.1) Inquiry
CDCS406231 Human PKP2 ORF Clone (BC126199) Inquiry
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