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RCHY1

Official Full Name
ring finger and CHY zinc finger domain containing 1
Organism
Homo sapiens
GeneID
25898
Background
The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2013]
Synonyms
ZCHY; ARNIP; CHIMP; PIRH2; RNF199; ZNF363; PRO1996;

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