Pages
Products

PHKB


Official Full Name
phosphorylase kinase regulatory subunit beta
Organism
Homo sapiens
Gene ID
5257
Background
Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency of liver and muscle. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. Two pseudogenes have been found on chromosomes 14 and 20, respectively.[provided by RefSeq, Feb 2010]
Synonyms
FRA

Cat.No. Product Name Price
SHH374892 shRNA set against Human PHKB (NM_000293.2) Inquiry
SHH374896 shRNA set against Mouse PHKB (NM_199446.1) Inquiry
SHH374900 shRNA set against Rat PHKB (NM_001014152.1) Inquiry
SHR111864 shRNA set against Mouse Phkb(NM_199446.1) Inquiry
SHW000699 shRNA set against Chicken PHKB (NM_001007831) Inquiry
Cat.No. Product Name Price
CDFR003279 Rat Phkb cDNA Clone(NM_001014152.1) Inquiry
MiUTR1M-09173 PHKB miRNA 3'UTR clone Inquiry
MiUTR1R-03216 PHKB miRNA 3'UTR clone Inquiry
CDCB162174 Chicken PHKB ORF Clone (NM_001007831) Inquiry
CDCB180308 Rabbit PHKB ORF clone (XM_008248371.1) Inquiry
CDCL148843 Human Phkb ORF clone (NM_199446.1) Inquiry
CDCR370286 Rat Phkb ORF Clone(NM_001014152.1) Inquiry
CDCS405556 Human PHKB ORF Clone (BC033657) Inquiry
Quick Inquiry