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PHKA2


Official Full Name
phosphorylase kinase regulatory subunit alpha 2
Organism
Homo sapiens
Gene ID
5256
Background
Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9A, also known as X-linked liver glycogenosis. Alternatively spliced transcript variants have been reported, but the full-length nature of these variants has not been determined.[provided by RefSeq, Feb 2010]
Synonyms
PHK; PYK; XLG; PYKL; XLG2; GSD9A

Cat.No. Product Name Price
SHH374880 shRNA set against Human PHKA2 (NM_000292.2) Inquiry
SHH374884 shRNA set against Mouse PHKA2 (NM_172783.3) Inquiry
SHH374888 shRNA set against Rat PHKA2 (NM_001190994.1) Inquiry
Cat.No. Product Name Price
MiUTR3H-02940 PHKA2 miRNA 3'UTR clone Inquiry
CDCB181038 Rabbit PHKA2 ORF clone (XM_008272347.1) Inquiry
CDCL151634 Human Phka2 ORF clone (NM_001177878.1) Inquiry
CDCR242857 Mouse Phka2 ORF Clone(NM_001177879.1) Inquiry
CDCR271637 Mouse Phka2 ORF Clone(NM_172783.3) Inquiry
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