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PHKA1


Official Full Name
phosphorylase kinase regulatory subunit alpha 1
Organism
Homo sapiens
Gene ID
5255
Background
Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the skeletal muscle isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9D, also known as X-linked muscle glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. A pseudogene has been found on chromosome 1.[provided by RefSeq, Feb 2010]
Synonyms
PHKA

Cat.No. Product Name Price
SHH374868 shRNA set against Human PHKA1 (NM_002637.3) Inquiry
SHH374872 shRNA set against Mouse PHKA1 (NM_173021.3) Inquiry
SHH374876 shRNA set against Rat PHKA1 (NM_022626.1) Inquiry
SHR098320 shRNA set against Rat Phka1(NM_022626.1) Inquiry
SHR111724 shRNA set against Mouse Phka1(NM_008832.2) Inquiry
SHR111738 shRNA set against Mouse Phka1(NM_173021.3) Inquiry
SHR111768 shRNA set against Mouse Phka1(NM_008832.2) Inquiry
SHR111816 shRNA set against Mouse Phka1(NM_173021.3) Inquiry
Cat.No. Product Name Price
CDCR271671 Mouse Phka1 ORF Clone(NM_173021.3) Inquiry
CDFH014209 Human PHKA1 cDNA Clone(NM_001122670.1) Inquiry
CDFH014210 Human PHKA1 cDNA Clone(NM_001172436.1) Inquiry
CDFL010235 Mouse Phka1 cDNA Clone(NM_008832.2) Inquiry
CDFL010236 Mouse Phka1 cDNA Clone(NM_173021.3) Inquiry
CDFR012057 Rat Phka1 cDNA Clone(NM_022626.1) Inquiry
MiUTR1M-09171 PHKA1 miRNA 3'UTR clone Inquiry
MiUTR1M-09172 PHKA1 miRNA 3'UTR clone Inquiry
MiUTR1R-05817 PHKA1 miRNA 3'UTR clone Inquiry
CDCB180309 Rabbit PHKA1 ORF clone (XM_008272695.1) Inquiry
CDCL148823 Human PHKA1 ORF clone (NM_001172436.1) Inquiry
CDCR245741 Mouse Phka1 ORF Clone(NM_008832.2) Inquiry
CDCR348244 Human PHKA1 ORF Clone(NM_001122670.1) Inquiry
CDCR379104 Rat Phka1 ORF Clone(NM_022626.1) Inquiry
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