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PHF8


Official Full Name
PHD finger protein 8
Organism
Homo sapiens
Gene ID
23133
Background
The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. The protein has an N-terminal PHD finger and a central Jumonji C domain. This gene is thought to function as a transcription activator. Defects in this gene are a cause of syndromic X-linked Siderius type intellectual disability (MRXSSD) and over-expression of this gene is associated with several forms of cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]
Synonyms
KDM7B; JHDM1F; MRXSSD; ZNF422

Cat.No. Product Name Price
SHH374832 shRNA set against Human PHF8 (NM_015107.2) Inquiry
SHR111614 shRNA set against Mouse Phf8(NM_177201.5) Inquiry
SHW013858 shRNA set against Danio rerio PHF8 (NM_001202447) Inquiry
Cat.No. Product Name Price
CDCG001013 Human PHF8 ORF clone(NM_015107.2) Inquiry
CDFG019181 Mouse Phf8 cDNA Clone(NM_001113354.1) Inquiry
CDFH014203 Human PHF8 cDNA Clone(NM_001184896.1) Inquiry
CDFH014204 Human PHF8 cDNA Clone(NM_001184898.1) Inquiry
CDFH014205 Human PHF8 cDNA Clone(NM_001184897.1) Inquiry
MiUTR1M-09167 PHF8 miRNA 3'UTR clone Inquiry
MiUTR4H-TG06645 PHF8 miRNA 3'UTR clone Inquiry
CDCB175333 Danio rerio PHF8 ORF Clone (NM_001202447) Inquiry
CDCB190899 Rabbit PHF8 ORF clone (XM_002720027.2) Inquiry
CDCL148799 Human PHF8 ORF clone (NM_001184898.1) Inquiry
CDCL148801 Mouse PHF8 ORF clone (NM_001184897.1) Inquiry
CDCL148803 Human PHF8 ORF clone (NM_001184896.1) Inquiry
CDCL148811 Human Phf8 ORF clone (NM_001113354.1) Inquiry
CDCR273623 Mouse Phf8 ORF Clone(NM_177201.5) Inquiry
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