Pages
Products

PGK1


Official Full Name
phosphoglycerate kinase 1
Organism
Homo sapiens
Gene ID
5230
Background
The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014]
Synonyms
PGKA; MIG10; HEL-S-68p

Cat.No. Product Name Price
SHH374256 shRNA set against Rat PGK1 (NM_053291.3) Inquiry
SHH374252 shRNA set against Mouse PGK1 (NM_008828.2) Inquiry
SHR109056 shRNA set against Mouse Pgk1(NM_008828.2) Inquiry
SHR109120 shRNA set against Rat Pgk1(NM_053291.3) Inquiry
SHW005486 shRNA set against Chicken PGK1 (NM_204985) Inquiry
SHW018450 shRNA set against Danio rerio PGK1 (NM_213387) Inquiry
Cat.No. Product Name Price
CDFR013051 Rat Pgk1 cDNA Clone(NM_053291.3) Inquiry
MiUTR1M-09144 PGK1 miRNA 3'UTR clone Inquiry
MiUTR1R-05794 PGK1 miRNA 3'UTR clone Inquiry
MiUTR3H-03000 PGK1 miRNA 3'UTR clone Inquiry
CDCB166961 Chicken PGK1 ORF Clone (NM_204985) Inquiry
CDCB179925 Danio rerio PGK1 ORF Clone (NM_213387) Inquiry
CDCB191620 Rabbit PGK1 ORF clone (XM_002720132.2) Inquiry
CDCL185699 Mouse PGK1 ORF clone(NM_008828.2) Inquiry
CDCR380098 Rat Pgk1 ORF Clone(NM_053291.3) Inquiry
CDCS405555 Human PGK1 ORF Clone (BC113568) Inquiry
Quick Inquiry