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PGEA1

Official Full Name
chibby 1, beta catenin antagonist
Organism
Homo sapiens
GeneID
25776
Background
Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
CBY1; CBY; arb1; PGEA1; C22orf2; Chibby1; PIGEA14; PIGEA-14; HS508I15A;

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