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Penk1


Official Full Name
preproenkephalin
Organism
Mus musculus
Gene ID
18619
Background
Enables opioid peptide activity and opioid receptor binding activity. Involved in G protein-coupled opioid receptor signaling pathway; regulation of long-term synaptic depression; and transmission of nerve impulse. Acts upstream of or within several processes, including behavioral fear response; sensory perception of pain; and startle response. Predicted to be located in several cellular components, including cell body fiber; perikaryon; and symmetric synapse. Predicted to be active in several cellular components, including axon terminus; cytoplasmic vesicle lumen; and neuronal cell body. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in overactive bladder syndrome. Orthologous to human PENK (proenkephalin). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Penk; ENK; PPA; Penk1

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