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PARP3

Official Full Name
poly(ADP-ribose) polymerase family member 3
Organism
Homo sapiens
GeneID
10039
Background
The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Synonyms
IRT1; ARTD3; ADPRT3; ADPRTL2; ADPRTL3; PADPRT-3;

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