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PAK7


Official Full Name
p21 (RAC1) activated kinase 5
Organism
Homo sapiens
Gene ID
57144
Background
The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
Synonyms
PAK5; PAK7

Cat.No. Product Name Price
SHH370216 shRNA set against Rat PAK7 (NM_001107781.1) Inquiry
SHR086160 shRNA set against Mouse Pak7(NM_172858.2) Inquiry
SHH370208 shRNA set against Human PAK7 (NM_177990.2) Inquiry
SHH370212 shRNA set against Mouse PAK7 (NM_172858.2) Inquiry
SHW003226 shRNA set against Chicken PAK7 (NM_001199409) Inquiry
SHW018097 shRNA set against Danio rerio PAK7 (NM_212962) Inquiry
Cat.No. Product Name Price
CDFL009863 Mouse Pak7 cDNA Clone(NM_172858.2) Inquiry
CDFR007409 Rat Pak7 cDNA Clone(NM_001107781.1) Inquiry
MiUTR1M-08874 PAK7 miRNA 3'UTR clone Inquiry
CDCB164701 Chicken PAK7 ORF Clone (NM_001199409) Inquiry
CDCB179572 Danio rerio PAK7 ORF Clone (NM_212962) Inquiry
CDCB193181 Rabbit PAK7 ORF clone (XM_002710976.2) Inquiry
CDCL185604 Human PAK7 ORF clone(NM_020341.3) Inquiry
CDCL185605 Mouse PAK7 ORF clone(NM_172858.2) Inquiry
CDCR374326 Rat Pak7 ORF Clone(NM_001107781.1) Inquiry
CDCS415049 Human PAK7 ORF Clone (BC024179) Inquiry
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