Pages
Products

PYHIN1


Official Full Name
pyrin and HIN domain family member 1
Organism
Homo sapiens
Gene ID
149628
Background
The protein encoded by this gene belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis. Downregulation of this gene is associated with breast cancer. This protein acts as a tumor suppressor by promoting ubiquitination and subsequent degradation of MDM2, which leads to stabilization of p53/TP53. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Synonyms
IFIX

Cat.No. Product Name Price
SHH387488 shRNA set against Human PYHIN1 (NM_152501.4) Inquiry
SHH387492 shRNA set against Mouse PYHIN1 (NM_175026.3) Inquiry
Cat.No. Product Name Price
MiUTR3H-12540 PYHIN1 miRNA 3'UTR clone Inquiry
MiUTR3H-12541 PYHIN1 miRNA 3'UTR clone Inquiry
MiUTR3H-12542 PYHIN1 miRNA 3'UTR clone Inquiry
MiUTR3H-12543 PYHIN1 miRNA 3'UTR clone Inquiry
CDCB157959 Human PYHIN1 ORF clone (BC139741) Inquiry
CDCR272463 Mouse Pyhin1 ORF Clone(NM_175026.3) Inquiry
CDCR326372 Human PYHIN1 ORF Clone(NM_198929.4) Inquiry
CDCS417169 Human PYHIN1 ORF Clone (BC020822) Inquiry
CDCS417170 Human PYHIN1 ORF Clone (BC139741) Inquiry
Quick Inquiry