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PVRL1


Official Full Name
nectin cell adhesion molecule 1
Organism
Homo sapiens
Gene ID
5818
Background
This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009]
Synonyms
NECTIN1; ED4; PRR; HIgR; HV1S; HVEC; OFC7; PRR1; PVRR; CD111; PVRL1; PVRR1; SK-12; CLPED1; nectin-1

Cat.No. Product Name Price
SHH387180 shRNA set against Human PVRL1 (NM_002855.4) Inquiry
SHH387184 shRNA set against Mouse PVRL1 (NM_021424.2) Inquiry
SHR155202 shRNA set against Human PVRL1(NM_203286.1) Inquiry
SHR155220 shRNA set against Human PVRL1(NM_002855.4) Inquiry
SHR155238 shRNA set against Human PVRL1(NM_203285.1) Inquiry
SHR155292 shRNA set against Mouse Pvrl1(NM_021424.2) Inquiry
Cat.No. Product Name Price
CDCS411010 Human PVRL1 ORF Clone (BC113471) Inquiry
CDFG013446 Human PVRL1 cDNA Clone(NM_203285.1) Inquiry
CDFG013451 Human PVRL1 cDNA Clone(NM_203286.1) Inquiry
CDFH015636 Human PVRL1 cDNA Clone(NM_002855.4) Inquiry
MiUTR1H-08502 PVRL1 miRNA 3'UTR clone Inquiry
MiUTR1H-08503 PVRL1 miRNA 3'UTR clone Inquiry
MiUTR1H-08504 PVRL1 miRNA 3'UTR clone Inquiry
MiUTR1M-09794 PVRL1 miRNA 3'UTR clone Inquiry
CDCB156864 Rat PVRL1 ORF clone (XM_236210.5) Inquiry
CDCB192811 Rabbit PVRL1 ORF clone (XM_008267208.1) Inquiry
CDCH070196 human PVRL1 ORF clone (NM_203285.1) Inquiry
CDCH070198 human PVRL1 ORF clone (NM_203286.1) Inquiry
CDCH070204 Mouse Pvrl1 ORF clone (NM_021424.2) Inquiry
CDCL185918 Human PVRL1 ORF clone(NM_002855.4) Inquiry
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