Pages
Products

PTPN13


Official Full Name
protein tyrosine phosphatase non-receptor type 13
Organism
Homo sapiens
Gene ID
5783
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Oct 2008]
Synonyms
PNP1; FAP-1; PTP1E; PTPL1; PTPLE; PTP-BL; hPTP1E; PTP-BAS

Cat.No. Product Name Price
SHH386456 shRNA set against Human PTPN13 (NM_006264.2) Inquiry
SHH386460 shRNA set against Mouse PTPN13 (NM_011204.2) Inquiry
SHW011514 shRNA set against Danio rerio PTPN13 (NM_001089543) Inquiry
Cat.No. Product Name Price
CDCR315024 Human PTPN13 ORF Clone(NM_080685.2) Inquiry
CDFL011041 Mouse Ptpn13 cDNA Clone(NM_011204.2) Inquiry
MiUTR1M-09756 PTPN13 miRNA 3'UTR clone Inquiry
MiUTR3H-03228 PTPN13 miRNA 3'UTR clone Inquiry
MiUTR3H-03229 PTPN13 miRNA 3'UTR clone Inquiry
MiUTR3H-03230 PTPN13 miRNA 3'UTR clone Inquiry
MiUTR3H-03231 PTPN13 miRNA 3'UTR clone Inquiry
CDCB172989 Danio rerio PTPN13 ORF Clone (NM_001089543) Inquiry
CDCB195592 Rabbit PTPN13 ORF clone (XM_008267634.1) Inquiry
CDCH069688 Mouse Ptpn13 ORF clone (NM_011204.2) Inquiry
CDCR033214 Human PTPN13 ORF clone (NM_080683.2) Inquiry
Quick Inquiry