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PSMD12


Official Full Name
proteasome 26S subunit, non-ATPase 12
Organism
Homo sapiens
Gene ID
5718
Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Synonyms
p55; Rpn5; STISS

Cat.No. Product Name Price
SHH385388 shRNA set against Mouse PSMD12 (NM_025894.2) Inquiry
SHH385384 shRNA set against Human PSMD12 (NM_002816.3) Inquiry
SHH385392 shRNA set against Rat PSMD12 (NM_001005875.1) Inquiry
SHR148362 shRNA set against Rat Psmd12(NM_001005875.1) Inquiry
SHR148398 shRNA set against Mouse Psmd12(NM_025894.2) Inquiry
SHR148416 shRNA set against Human PSMD12(NM_002816.3) Inquiry
SHW001350 shRNA set against Chicken PSMD12 (NM_001030706) Inquiry
SHW017446 shRNA set against Danio rerio PSMD12 (NM_201578) Inquiry
Cat.No. Product Name Price
CDCB162825 Chicken PSMD12 ORF Clone (NM_001030706) Inquiry
CDCB178921 Danio rerio PSMD12 ORF Clone (NM_201578) Inquiry
CDFH015390 Human PSMD12 cDNA Clone(NM_002816.3) Inquiry
CDFR001314 Rat Psmd12 cDNA Clone(NM_001005875.1) Inquiry
MiUTR1H-08386 PSMD12 miRNA 3'UTR clone Inquiry
MiUTR1M-09699 PSMD12 miRNA 3'UTR clone Inquiry
MiUTR1R-06154 PSMD12 miRNA 3'UTR clone Inquiry
MiUTR3H-06813 PSMD12 miRNA 3'UTR clone Inquiry
CDCB159229 Human PSMD12 ORF clone (BC019062) Inquiry
CDCB194642 Rabbit PSMD12 ORF clone (XM_008271732.1) Inquiry
CDCH069122 human PSMD12 ORF clone (NM_174871.2) Inquiry
CDCR284137 Human PSMD12 ORF Clone(NM_002816.3) Inquiry
CDCR368555 Rat Psmd12 ORF Clone(NM_001005875.1) Inquiry
CDCS410985 Human PSMD12 ORF Clone (BC019062) Inquiry
CDCS410986 Human PSMD12 ORF Clone (BC065826) Inquiry
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