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PRPH2


Official Full Name
peripherin 2
Organism
Homo sapiens
Gene ID
5961
Background
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein found in the outer segment of both rod and cone photoreceptor cells. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. This protein is essential for disk morphogenesis. Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically different disorders are autosomal dominant retinitis pigmentosa, progressive macular degeneration, macular dystrophy and retinitis pigmentosa digenic. [provided by RefSeq, Jul 2008]
Synonyms
DS; RDS; RP7; rd2; AVMD; PRPH; AOFMD; CACD2; MDBS1; TSPAN22

Cat.No. Product Name Price
SHH383860 shRNA set against Human PRPH2 (NM_000322.4) Inquiry
SHH383864 shRNA set against Mouse PRPH2 (NM_008938.1) Inquiry
SHH383868 shRNA set against Rat PRPH2 (NM_013021.1) Inquiry
SHR143230 shRNA set against Mouse Prph2(NM_008938.1) Inquiry
SHR143266 shRNA set against Rat Rds(NM_013021.1) Inquiry
SHW005538 shRNA set against Chicken PRPH2 (NM_205038) Inquiry
Cat.No. Product Name Price
CDFR010826 Rat Prph2 cDNA Clone(NM_013021.1) Inquiry
MiUTR1M-09632 PRPH2 miRNA 3'UTR clone Inquiry
MiUTR1R-06362 PRPH2 miRNA 3'UTR clone Inquiry
MiUTR3H-01995 PRPH2 miRNA 3'UTR clone Inquiry
CDCB167013 Chicken PRPH2 ORF Clone (NM_205038) Inquiry
CDCB192839 Rabbit PRPH2 ORF clone (XM_002714408.2) Inquiry
CDCH068362 Mouse Prph2 ORF clone (NM_008938.1) Inquiry
CDCH395391 Human PRPH2 ORF clone(NM_000322.4) Inquiry
CDCR377903 Rat Prph2 ORF Clone(NM_013021.1) Inquiry
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