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PROL1


Official Full Name
opiorphin prepropeptide
Organism
Homo sapiens
Gene ID
58503
Background
This gene encodes a member of the proline-rich protein family. The encoded protein has multiple proposed functions, including roles in pain suppression, penile erection, and protection of the eye surface. The QRFSR pentapeptide, known as opiorphin, is derived from the N-terminal of this protein. Opiorphin inhibits the enkephalin-inactivating peptidases neprilysin and aminopeptidase N, and this activity is thought to reduce sensitivity to painful stimuli by effecting enkephalin-related activation of opioid-dependent pathways. Opiorphin may also act as an anti-depressant. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Synonyms
OPRPN; BPLP; PRL1; PROL1; opiorphin

Cat.No. Product Name Price
SHH383544 shRNA set against Human PROL1 (NM_021225.4) Inquiry
SHH383548 shRNA set against Mouse PROL1 (NM_008644.2) Inquiry
SHH383552 shRNA set against Rat PROL1 (NM_133513.1) Inquiry
Cat.No. Product Name Price
CDFG003294 Human PROL1 cDNA Clone(NM_021225.4) Inquiry
CDFL010835 Mouse Prol1 cDNA Clone(NM_008644.2) Inquiry
CDFR014033 Rat Prol1 cDNA Clone(NM_133513.1) Inquiry
MiUTR1H-08310 PROL1 miRNA 3'UTR clone Inquiry
MiUTR1M-07387 PROL1 miRNA 3'UTR clone Inquiry
MiUTR1R-04053 PROL1 miRNA 3'UTR clone Inquiry
CDCH068180 Mouse Prol1 ORF clone (NM_008644.2) Inquiry
CDCL185858 Human PROL1 ORF clone(NM_021225.4) Inquiry
CDCR381088 Rat Prol1 ORF Clone(NM_133513.1) Inquiry
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