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PRMT6


Official Full Name
protein arginine methyltransferase 6
Organism
Homo sapiens
Gene ID
55170
Background
The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011]
Synonyms
HRMT1L6

Cat.No. Product Name Price
SHH383368 shRNA set against Human PRMT6 (NM_018137.2) Inquiry
SHH383372 shRNA set against Mouse PRMT6 (NM_178891.4) Inquiry
SHH383376 shRNA set against Rat PRMT6 (NM_001106466.1) Inquiry
SHW013453 shRNA set against Danio rerio PRMT6 (NM_001163988) Inquiry
Cat.No. Product Name Price
CDCL185848 Mouse PRMT6 ORF clone(NM_178891.4) Inquiry
CDFG001283 Human PRMT6 cDNA Clone(NM_018137.2) Inquiry
CDFR006201 Rat Prmt6 cDNA Clone(NM_001106466.1) Inquiry
MiUTR1M-09607 PRMT6 miRNA 3'UTR clone Inquiry
MiUTR3H-09882 PRMT6 miRNA 3'UTR clone Inquiry
CDCB174928 Danio rerio PRMT6 ORF Clone (NM_001163988) Inquiry
CDCB189986 Rabbit PRMT6 ORF clone (XM_008264786.1) Inquiry
CDCL185847 Human PRMT6 ORF clone(NM_018137.2) Inquiry
CDCR373253 Rat Prmt6 ORF Clone(NM_001106466.1) Inquiry
CDCS414660 Human PRMT6 ORF Clone (BC063446) Inquiry
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