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PRKCI


Official Full Name
protein kinase C iota
Organism
Homo sapiens
Gene ID
5584
Background
This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X. [provided by RefSeq, Jul 2008]
Synonyms
PKCI; DXS1179E; nPKC-iota

Cat.No. Product Name Price
SHH382868 shRNA set against Mouse PRKCI (NM_008857.3) Inquiry
SHH382872 shRNA set against Rat PRKCI (NM_032059.1) Inquiry
SHR140596 shRNA set against Human PRKCI(NM_002740.5) Inquiry
SHR140646 shRNA set against Mouse Prkci(NM_008857.3) Inquiry
SHW001915 shRNA set against Chicken PRKCI (NM_001031319) Inquiry
SHW015246 shRNA set against Danio rerio PRKCI (NM_131855) Inquiry
Cat.No. Product Name Price
CDFH015129 Human PRKCI cDNA Clone(NM_002740.5) Inquiry
CDFR012997 Rat Prkci cDNA Clone(NM_032059.1) Inquiry
MiUTR1H-08277 PRKCI miRNA 3'UTR clone Inquiry
MiUTR1M-09581 PRKCI miRNA 3'UTR clone Inquiry
SKO0096 PRKCI Validated sgRNA vector Inquiry
CDCB163390 Chicken PRKCI ORF Clone (NM_001031319) Inquiry
CDCB176721 Danio rerio PRKCI ORF Clone (NM_131855) Inquiry
CDCB188688 Rabbit PRKCI ORF clone (XM_008266470.1) Inquiry
CDCL185830 Human PRKCI ORF clone(NM_002740.5) Inquiry
CDCL185831 Mouse PRKCI ORF clone(NM_008857.3) Inquiry
CDCR380011 Rat Prkci ORF Clone(NM_032059.1) Inquiry
CDCS410932 Human PRKCI ORF Clone (BC022016) Inquiry
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