Pages
Products

PRKAB1


Official Full Name
protein kinase AMP-activated non-catalytic subunit beta 1
Organism
Homo sapiens
Gene ID
5564
Background
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008]
Synonyms
AMPK; HAMPKb

Cat.No. Product Name Price
SHR139224 shRNA set against Human PRKAB1(NM_006253.4) Inquiry
SHH382648 shRNA set against Human PRKAB1 (NM_006253.4) Inquiry
SHH382652 shRNA set against Mouse PRKAB1 (NM_031869.2) Inquiry
SHH382656 shRNA set against Rat PRKAB1 (NM_031976.1) Inquiry
SHR139496 shRNA set against Rat Prkab1(NM_031976.1) Inquiry
SHR139514 shRNA set against Mouse Prkab1(NM_031869.2) Inquiry
SHW002345 shRNA set against Chicken PRKAB1 (NM_001039912) Inquiry
Cat.No. Product Name Price
CDFH015093 Human PRKAB1 cDNA Clone(NM_006253.4) Inquiry
CDFR012982 Rat Prkab1 cDNA Clone(NM_031976.1) Inquiry
MiUTR1M-09570 PRKAB1 miRNA 3'UTR clone Inquiry
MiUTR1R-06046 PRKAB1 miRNA 3'UTR clone Inquiry
MiUTR3H-05279 PRKAB1 miRNA 3'UTR clone Inquiry
CDCB163820 Chicken PRKAB1 ORF Clone (NM_001039912) Inquiry
CDCB188571 Rabbit PRKAB1 ORF clone (XM_002719800.2) Inquiry
CDCH067724 Mouse Prkab1 ORF clone (NM_031869.2) Inquiry
CDCL185815 Human PRKAB1 ORF clone(NM_006253.4) Inquiry
CDCR379996 Rat Prkab1 ORF Clone(NM_031976.1) Inquiry
Quick Inquiry