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prickle1a


Official Full Name
prickle homolog 1a
Organism
Danio rerio
Gene ID
368249
Background
Predicted to enable zinc ion binding activity. Involved in convergent extension involved in gastrulation and neuron migration. Acts upstream of or within several processes, including Kupffer's vesicle development; determination of left/right symmetry; and nervous system development. Predicted to be located in endomembrane system and membrane. Is expressed in several structures, including central nervous system; ectoderm; eye; mesoderm; and pharyngeal arch. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 1B. Orthologous to human PRICKLE1 (prickle planar cell polarity protein 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
pk1; fk71b09; prickle1; wu:fk71b09

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