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PPP1R8

Official Full Name
protein phosphatase 1 regulatory subunit 8
Organism
Homo sapiens
GeneID
5511
Background
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008]
Synonyms
ARD1; ARD-1; NIPP1; NIPP-1; PRO2047;

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