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PPIB

Official Full Name
peptidylprolyl isomerase B
Organism
Homo sapiens
GeneID
5479
Background
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009]
Synonyms
OI9; CYPB; SCYLP; CYP-S1; HEL-S-39;

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