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POFUT1

Official Full Name
protein O-fucosyltransferase 1
Organism
Homo sapiens
GeneID
23509
Background
This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Synonyms
DDD2; FUT12; O-FUT; OFUCT1; O-Fuc-T; O-FucT-1;

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