Pages
Products

PNPLA1


Official Full Name
patatin like phospholipase domain containing 1
Organism
Homo sapiens
Gene ID
285848
Background
The protein encoded by this gene belongs to the patatin-like phospholipase (PNPLA) family, which is characterized by the presence of a highly conserved patatin domain. PNPLA family members have diverse lipolytic and acyltransferase activities, and are key elements in lipid metabolism. While other members of this family have been well characterized, the function of this gene remained an enigma. However, recent studies show that this gene is expressed in the skin epidermal keratinocytes, and has a role in glycerophospholipid metabolism in the cutaneous barrier. Consistent with these observations, mutations in this gene are associated with ichthyosis in human (autosomal recessive congenital ichthyoses, ARCI) and dog. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
Synonyms
ARCI10; dJ50J22.1

Cat.No. Product Name Price
SHH378776 shRNA set against Human PNPLA1 (NM_173676.2) Inquiry
SHR125196 shRNA set against Mouse Pnpla1(NM_001034885.3) Inquiry
Cat.No. Product Name Price
CDFH014628 Human PNPLA1 cDNA Clone(NM_001145717.1) Inquiry
MiUTR1M-09375 PNPLA1 miRNA 3'UTR clone Inquiry
MiUTR4H-TG06829 PNPLA1 miRNA 3'UTR clone Inquiry
CDCB193693 Rabbit PNPLA1 ORF clone (XM_008262834.1) Inquiry
CDCH065512 human PNPLA1 ORF clone (NM_001145717.1) Inquiry
CDCH065514 human PNPLA1 ORF clone (NM_173676.2) Inquiry
CDCH065518 Mouse Pnpla1 ORF clone (NM_001034885.3) Inquiry
CDCR353018 Human PNPLA1 ORF Clone(NM_001145716.2) Inquiry
CDCS408543 Human PNPLA1 ORF Clone (BC103907) Inquiry
Quick Inquiry