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PNMA3

Official Full Name
paraneoplastic antigen MA3
Background
This gene is a member of the paraneoplastic antigen MA (PNMA) gene family, whose protein products share homology with retroviral Gag proteins. They are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3 by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized.
Synonyms
PNMA3; paraneoplastic antigen MA3; MA3; MA5; MGC132756; MGC132758; paraneoplastic cancer testis brain antigen; PNMA 3; PNMA3_HUMAN; paraneoplastic cancer-testis-brain antigen

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