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PLK3


Official Full Name
polo like kinase 3
Organism
Homo sapiens
Gene ID
1263
Background
The protein encoded by this gene is a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain and a carboxy-terminal bipartite polo box domain that functions as a substrate-binding motif and a cellular localization signal. Polo-like kinases are important regulators of cell cycle progression. This gene has also been implicated in stress responses and double-strand break repair. In human cell lines, this protein is reported to associate with centrosomes in a microtubule-dependent manner, and during mitosis, the protein becomes localized to the mitotic apparatus. Expression of a kinase-defective mutant results in abnormal cell morphology caused by changes in microtubule dynamics and mitotic arrest followed by apoptosis. [provided by RefSeq, Sep 2015]
Synonyms
CNK; FNK; PRK; PLK-3

Cat.No. Product Name Price
SHH377916 shRNA set against Human PLK3 (NM_004073.2) Inquiry
SHH377920 shRNA set against Mouse PLK3 (NM_013807.2) Inquiry
SHH377924 shRNA set against Rat PLK3 (NM_022187.1) Inquiry
SHR122688 shRNA set against Human PLK3(NM_004073.2) Inquiry
SHR122836 shRNA set against Mouse Plk3(NM_013807.2) Inquiry
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Cat.No. Product Name Price
CDFH014536 Human PLK3 cDNA Clone(NM_004073.2) Inquiry
CDFH014537 Human PLK3 cDNA Clone(NM_004073.2) Inquiry
CDFR011820 Rat Plk3 cDNA Clone(NM_022187.1) Inquiry
MiUTR1H-08010 PLK3 miRNA 3'UTR clone Inquiry
MiUTR1M-09338 PLK3 miRNA 3'UTR clone Inquiry
CDCB178817 Danio rerio PLK3 ORF Clone (NM_201308) Inquiry
CDCB188367 Rabbit PLK3 ORF clone (XM_002715146.2) Inquiry
CDCL185749 Human PLK3 ORF clone(NM_004073.2) Inquiry
CDCR252425 Mouse Plk3 ORF Clone(NM_013807.2) Inquiry
CDCR378878 Rat Plk3 ORF Clone(NM_022187.1) Inquiry
CDCS411593 Human PLK3 ORF Clone (BC013899) Inquiry
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