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PKD2

Official Full Name
polycystin 2, transient receptor potential cation channel
Organism
Homo sapiens
GeneID
5311
Background
This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011]
Synonyms
PC2; PKD4; Pc-2; APKD2; TRPP2;

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