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PILRA


Official Full Name
paired immunoglobin like type 2 receptor alpha
Organism
Homo sapiens
Gene ID
29992
Background
Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described. [provided by RefSeq, Jul 2008]
Synonyms
FDF03

Cat.No. Product Name Price
SHH375856 shRNA set against Human PILRA (NM_178273.1) Inquiry
SHH375860 shRNA set against Mouse PILRA (NM_153510.3) Inquiry
SHR114972 shRNA set against Human PILRA(NM_013439.2) Inquiry
SHR115022 shRNA set against Human PILRA(NM_178272.1) Inquiry
SHR115058 shRNA set against Human PILRA(NM_178273.1) Inquiry
Cat.No. Product Name Price
CDCB159697 Human PILRA ORF clone (BC017812) Inquiry
CDCH063940 human PILRA ORF clone (NM_178273.1) Inquiry
CDFG011535 Human PILRA cDNA Clone(NM_178272.1) Inquiry
CDFG011540 Human PILRA cDNA Clone(NM_178273.1) Inquiry
CDFH014318 Human PILRA cDNA Clone(NM_013439.2) Inquiry
MiUTR1H-07917 PILRA miRNA 3'UTR clone Inquiry
MiUTR1H-07918 PILRA miRNA 3'UTR clone Inquiry
MiUTR1H-07919 PILRA miRNA 3'UTR clone Inquiry
CDCB157293 Mouse PILRA ORF clone (NM_153510.2) Inquiry
CDCB193456 Rabbit PILRA ORF clone (XM_008258032.1) Inquiry
CDCH063938 human PILRA ORF clone (NM_178272.1) Inquiry
CDCH063942 human PILRA ORF clone (NM_013439.2) Inquiry
CDCR270384 Mouse Pilra ORF Clone(NM_153510.3) Inquiry
CDCS413450 Human PILRA ORF Clone (BC017812) Inquiry
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