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phox2bb


Official Full Name
paired like homeobox 2Bb
Organism
Danio rerio
Gene ID
544654
Background
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within axonogenesis; enteric nervous system development; and sympathetic ganglion development. Predicted to be located in nucleus. Is expressed in several structures, including digestive system; mesenchyme pectoral fin; nervous system; neuroepithelial cell; and presumptive enteric nervous system. Human ortholog(s) of this gene implicated in colorectal cancer; congenital central hypoventilation syndrome; and neuroblastoma. Orthologous to human PHOX2B (paired like homeobox 2B). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
phox2b

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CDCB169649 Danio rerio PHOX2BB ORF Clone (NM_001014818) Inquiry
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