Pages
Products

PGC


Official Full Name
progastricsin
Organism
Homo sapiens
Gene ID
5225
Background
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]
Synonyms
PEPC; PGII

Cat.No. Product Name Price
SHH374184 shRNA set against Human PGC (NM_002630.3) Inquiry
SHH374188 shRNA set against Mouse PGC (NM_025973.3) Inquiry
SHH374192 shRNA set against Rat PGC (NM_133284.2) Inquiry
SHR108762 shRNA set against Mouse Pgc(NM_025973.3) Inquiry
SHW005383 shRNA set against Chicken PGC (NM_204877) Inquiry
Cat.No. Product Name Price
CDCL148415 Human PGC ORF clone (NM_001166424.1) Inquiry
CDCS408847 Human PGC ORF Clone (BC042578) Inquiry
CDFH014152 Human PGC cDNA Clone(NM_001166424.1) Inquiry
MiUTR1M-09137 PGC miRNA 3'UTR clone Inquiry
MiUTR3H-01685 PGC miRNA 3'UTR clone Inquiry
CDCB166858 Chicken PGC ORF Clone (NM_204877) Inquiry
CDCB180969 Rabbit PGC ORF clone (XM_008263264.1) Inquiry
CDCG000599 Mouse PGC ORF clone(NM_025973.3) Inquiry
CDCL185695 Human PGC ORF clone(NM_002630.3) Inquiry
CDCL185696 Mouse PGC ORF clone(NM_133284.2) Inquiry
Quick Inquiry