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PFKFB1


Official Full Name
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Organism
Homo sapiens
Gene ID
5207
Background
This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012]
Synonyms
F6PK; HL2K; PFRX

Cat.No. Product Name Price
SHH373912 shRNA set against Mouse PFKFB1 (NM_008824.2) Inquiry
SHH373916 shRNA set against Rat PFKFB1 (NM_012621.4) Inquiry
SHR107484 shRNA set against Human PFKFB1(NM_002625.2) Inquiry
SHR107502 shRNA set against Mouse Pfkfb1(NM_008824.2) Inquiry
SHR107538 shRNA set against Rat Pfkfb1(NM_012621.4) Inquiry
SHW016078 shRNA set against Danio rerio PFKFB1 (NM_199808) Inquiry
Cat.No. Product Name Price
CDFR010440 Rat Pfkfb1 cDNA Clone(NM_012621.4) Inquiry
MiUTR1H-07799 PFKFB1 miRNA 3'UTR clone Inquiry
MiUTR1M-09128 PFKFB1 miRNA 3'UTR clone Inquiry
MiUTR1R-05774 PFKFB1 miRNA 3'UTR clone Inquiry
CDCB177553 Danio rerio PFKFB1 ORF Clone (NM_199808) Inquiry
CDCB190751 Rabbit PFKFB1 ORF clone (XM_008272667.1) Inquiry
CDCL148267 Mouse PFKFB1 ORF clone (NM_002625.2) Inquiry
CDCL148269 Mouse Pfkfb1 ORF clone (NM_008824.2) Inquiry
CDCR377487 Rat Pfkfb1 ORF Clone(NM_012621.4) Inquiry
CDCS410198 Human PFKFB1 ORF Clone (BC096079) Inquiry
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