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PEX14

Official Full Name
peroxisomal biogenesis factor 14
Organism
Homo sapiens
GeneID
5195
Background
This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq, Jul 2008]
Synonyms
NAPP2; PBD13A; Pex14p; dJ734G22.2;

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