Pages
Products

PEO1


Official Full Name
twinkle mtDNA helicase
Organism
Homo sapiens
Gene ID
56652
Background
This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Aug 2009]
Synonyms
TWNK; PEO; PEO1; SCA8; ATXN8; IOSCA; PEOA3; SANDO; TWINL; MTDPS7; PRLTS5; C10orf2

Cat.No. Product Name Price
SHH373516 shRNA set against Mouse Peo1 (NM_153796.3) Inquiry
SHH373520 shRNA set against Rat Peo1 (NM_001107599.1) Inquiry
SHR095492 shRNA set against Mouse Peo1(NM_153796.3) Inquiry
SHW001940 shRNA set against Chicken PEO1 (NM_001031344) Inquiry
SHW014186 shRNA set against Danio rerio PEO1 (NM_001277598) Inquiry
Cat.No. Product Name Price
CDFR007247 Rat Peo1 cDNA Clone(NM_001107599.1) Inquiry
MiUTR1M-09106 PEO1 miRNA 3'UTR clone Inquiry
CDCB163415 Chicken PEO1 ORF Clone (NM_001031344) Inquiry
CDCB175661 Danio rerio PEO1 ORF Clone (NM_001277598) Inquiry
CDCL148049 Human Peo1 ORF clone (NM_153796.3) Inquiry
CDCR374334 Rat Peo1 ORF Clone(NM_001107599.1) Inquiry
Quick Inquiry