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PELI1

Official Full Name
pellino E3 ubiquitin protein ligase 1
Organism
Homo sapiens
GeneID
57162
Background
Enables ubiquitin-ubiquitin ligase activity. Involved in several processes, including negative regulation of TORC1 signaling; negative regulation of necroptotic process; and protein polyubiquitination. Is active in site of double-strand break. Implicated in colorectal cancer. [provided by Alliance of Genome Resources, Feb 2025]

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