Pages
Products

PCBP2


Official Full Name
poly(rC) binding protein 2
Organism
Homo sapiens
Gene ID
5094
Background
The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. This gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2018]
Synonyms
HNRPE2; HNRNPE2; hnRNP-E2

Cat.No. Product Name Price
AD11869Z Human PCBP2 adenoviral particles Inquiry
Cat.No. Product Name Price
SHH371384 shRNA set against Human PCBP2 (NM_005016.5) Inquiry
SHH371388 shRNA set against Rat PCBP2 (NM_001013223.1) Inquiry
SHR090780 shRNA set against Mouse Pcbp2(NM_011042.2) Inquiry
SHR090834 shRNA set against Rat Pcbp2(NM_001013223.1) Inquiry
SHR090852 shRNA set against Human PCBP2(NM_005016.5) Inquiry
SHR090888 shRNA set against Human PCBP2(NM_001098620.2) Inquiry
SHW017295 shRNA set against Danio rerio PCBP2 (NM_201192) Inquiry
Cat.No. Product Name Price
CDFG021288 Mouse Pcbp2 cDNA Clone(NM_001174073.1) Inquiry
MiUTR3H-03952 PCBP2 miRNA 3'UTR clone Inquiry
MiUTR3H-03951 PCBP2 miRNA 3'UTR clone Inquiry
MiUTR3H-03950 PCBP2 miRNA 3'UTR clone Inquiry
MiUTR1R-05643 PCBP2 miRNA 3'UTR clone Inquiry
MiUTR1M-08936 PCBP2 miRNA 3'UTR clone Inquiry
MiUTR1H-07556 PCBP2 miRNA 3'UTR clone Inquiry
MiUTR1H-07555 PCBP2 miRNA 3'UTR clone Inquiry
CDFR002895 Rat Pcbp2 cDNA Clone(NM_001013223.1) Inquiry
CDFL009943 Mouse Pcbp2 cDNA Clone(NM_011042.2) Inquiry
CDFH013783 Human PCBP2 cDNA Clone(NM_001128914.1) Inquiry
CDFH013782 Human PCBP2 cDNA Clone(NM_001128912.1) Inquiry
CDFH013781 Human PCBP2 cDNA Clone(NM_001128913.1) Inquiry
CDFH013780 Human PCBP2 cDNA Clone(NM_001128911.1) Inquiry
MiUTR3H-03953 PCBP2 miRNA 3'UTR clone Inquiry
MiUTR3H-03955 PCBP2 miRNA 3'UTR clone Inquiry
CDCS407444 Human PCBP2 ORF Clone (BC001155) Inquiry
CDCR369981 Rat Pcbp2 ORF Clone(NM_001013223.1) Inquiry
CDCR348847 Human PCBP2 ORF Clone(NM_001128911.1) Inquiry
CDCR250005 Mouse Pcbp2 ORF Clone(NM_011042.2) Inquiry
CDCR242257 Mouse Pcbp2 ORF Clone(NM_001174073.1) Inquiry
CDCL146419 Human PCBP2 ORF clone (NM_001098620.2) Inquiry
CDCL146417 Human PCBP2 ORF clone (NM_005016.5) Inquiry
CDCL146415 Human PCBP2 ORF clone (NM_001128912.1) Inquiry
CDCL146413 Human PCBP2 ORF clone (NM_001128913.1) Inquiry
CDCL146411 Human PCBP2 ORF clone (NM_001128914.1) Inquiry
CDCL146405 Human Pcbp2 ORF clone (NM_001103165.1) Inquiry
CDCL146403 Human Pcbp2 ORF clone (NM_001103166.1) Inquiry
CDCB183487 Rabbit PCBP2 ORF clone (XM_008256526.1) Inquiry
CDCS407445 Human PCBP2 ORF Clone (BC071942) Inquiry
CDCB178770 Danio rerio PCBP2 ORF Clone (NM_201192) Inquiry
Quick Inquiry