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PBRM1

Official Full Name
polybromo 1
Organism
Homo sapiens
GeneID
55193
Background
This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma. [provided by RefSeq, Feb 2012]
Synonyms
PB1; RCC; BAF180; SMARCH1;

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