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pax2a

Official Full Name
paired box 2a
Organism
Danio rerio
GeneID
30425
Background
Enables sequence-specific DNA binding activity. Involved in nervous system development. Acts upstream of or within several processes, including embryonic organ morphogenesis; nervous system development; and pronephros development. Located in nucleus. Is expressed in several structures, including immature eye; mesoderm; nervous system; neural keel; and pronephros. Used to study coloboma. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 7; renal Wilms' tumor; and renal coloboma syndrome. Orthologous to human PAX2 (paired box 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
noi; paxb; Pax-2; cb378; pax-b; pax2.1; pax2a1; PAXZF-B; pax[zf-b];

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