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PAX1

Official Full Name
paired box 1
Background
This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically;contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development.;This gene plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral;column. This gene is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene.;Mutations in this gene are also associated with vertebral malformations.
Synonyms
PAX1; paired box 1; paired box gene 1; paired box protein Pax-1; HUP48; OTTHUMP00000030407; Paired box protein Pax 1; Paired domain gene HuP48; PAX 1; PAX1_HUMAN; OTTHUMP00000206906

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