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PATZ1


Official Full Name
POZ/BTB and AT hook containing zinc finger 1
Organism
Homo sapiens
Gene ID
23598
Background
The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. [provided by RefSeq, Jul 2008]
Synonyms
ZSG; MAZR; PATZ; RIAZ; ZBTB19; ZNF278; dJ400N23

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Cat.No. Product Name Price
CDFG005653 Human PATZ1 cDNA Clone(NM_032050.1) Inquiry
CDFG005654 Human PATZ1 cDNA Clone(NM_032051.1) Inquiry
CDFG005655 Human PATZ1 cDNA Clone(NM_032052.1) Inquiry
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MiUTR1H-07530 PATZ1 miRNA 3'UTR clone Inquiry
MiUTR1H-07531 PATZ1 miRNA 3'UTR clone Inquiry
MiUTR1H-07532 PATZ1 miRNA 3'UTR clone Inquiry
MiUTR1H-07533 PATZ1 miRNA 3'UTR clone Inquiry
CDCB195129 Rabbit PATZ1 ORF clone (NM_001171351.1) Inquiry
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CDCL146187 Human PATZ1 ORF clone (NM_014323.2) Inquiry
CDCL146189 Human PATZ1 ORF clone (NM_032052.1) Inquiry
CDCL146191 Human PATZ1 ORF clone (NM_032050.1) Inquiry
CDCL146193 Human PATZ1 ORF clone (NM_032051.1) Inquiry
CDCR254063 Mouse Patz1 ORF Clone(NM_019574.3) Inquiry
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