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PARS2

Official Full Name
prolyl-tRNA synthetase 2, mitochondrial
Organism
Homo sapiens
GeneID
25973
Background
This gene encodes a putative member of the class II family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of proline to tRNA molecules. Mutations have been found in this gene in some patients with Alpers syndrome. [provided by RefSeq, Mar 2015]
Synonyms
DEE75; proRS; EIEE75; MT-PRORS;

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