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PAPPA2

Official Full Name
pappalysin 2
Organism
Homo sapiens
GeneID
60676
Background
This gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin-like growth factor-binding protein 5 and is thought to be a local regulator of insulin-like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]
Synonyms
SSDA; PAPPE; PLAC3; PAPP-E; PAPP-A2;

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