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OTOP1


Official Full Name
otopetrin 1
Organism
Homo sapiens
Gene ID
133060
Background
This gene encodes a transmembrane protein which belongs to the otopetrin domain protein family and is required for the formation of otoconia and otoliths, calcium carbonate biominerals within the inner ear of mammals that are required for the detection of linear acceleration and gravity. This gene modulates purinergic control of intracellular calcium in vestibular supporting cells. Naturally occurring mutations in the orthologous mouse gene are associated with nonsyndromic otoconia agenesis and a consequent balance defect. The orthologous mouse gene is also induced in white adipose tissue during obesity. The encoded protein is a component of a counterinflammatory pathway that attenuates obesity-induced adipose tissue inflammation and plays an adaptive role in maintaining metabolic homeostasis in obesity. [provided by RefSeq, Jul 2017]
Synonyms
MEL1; KMT8F; LVNC8; PFM13; CMD1LL

Cat.No. Product Name Price
SHH369000 shRNA set against Mouse OTOP1 (NM_172709.3) Inquiry
SHH368996 shRNA set against Human OTOP1 (NM_177998.1) Inquiry
SHH369004 shRNA set against Rat OTOP1 (NM_181433.1) Inquiry
SHR083144 shRNA set against Rat Otop1(NM_181433.1) Inquiry
SHR083270 shRNA set against Human OTOP1(NM_177998.1) Inquiry
SHR083310 shRNA set against Mouse Otop1(NM_172709.3) Inquiry
SHW015724 shRNA set against Danio rerio OTOP1 (NM_198803) Inquiry
Cat.No. Product Name Price
CDFG011452 Human OTOP1 cDNA Clone(NM_177998.1) Inquiry
CDFL009781 Mouse Otop1 cDNA Clone(NM_172709.3) Inquiry
CDFR014972 Rat Otop1 cDNA Clone(NM_181433.1) Inquiry
MiUTR1H-07411 OTOP1 miRNA 3'UTR clone Inquiry
MiUTR1M-08777 OTOP1 miRNA 3'UTR clone Inquiry
MiUTR1R-05567 OTOP1 miRNA 3'UTR clone Inquiry
CDCB177199 Danio rerio OTOP1 ORF Clone (NM_198803) Inquiry
CDCB188706 Rabbit OTOP1 ORF clone (XM_008251293.1) Inquiry
CDCL145051 Mouse OTOP1 ORF clone (NM_177998.1) Inquiry
CDCR271496 Mouse Otop1 ORF Clone(NM_172709.3) Inquiry
CDCR382019 Rat Otop1 ORF Clone(NM_181433.1) Inquiry
CDCS417563 Human OTOP1 ORF Clone (BC130430) Inquiry
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