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OPTN


Official Full Name
optineurin
Organism
Homo sapiens
Gene ID
10133
Background
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Synonyms
NRP; FIP2; HIP7; HYPL; ALS12; GLC1E; TFIIIA-INTP

Cat.No. Product Name Price
SHH366768 shRNA set against Human OPTN (NM_021980.4) Inquiry
SHH366772 shRNA set against Mouse OPTN (NM_181848.4) Inquiry
SHH366776 shRNA set against Rat OPTN (NM_145081.3) Inquiry
SHR071660 shRNA set against Rat Optn(NM_145081.3) Inquiry
SHR071814 shRNA set against Mouse Optn(NM_181848.4) Inquiry
SHR071850 shRNA set against Human OPTN(NM_001008211.1) Inquiry
SHW004752 shRNA set against Chicken OPTN (NM_204236) Inquiry
SHW011740 shRNA set against Danio rerio OPTN (NM_001100066) Inquiry
Cat.No. Product Name Price
MiUTR3H-04983 OPTN miRNA 3'UTR clone Inquiry
MiUTR3H-04981 OPTN miRNA 3'UTR clone Inquiry
MiUTR1R-05552 OPTN miRNA 3'UTR clone Inquiry
MiUTR1M-08740 OPTN miRNA 3'UTR clone Inquiry
CDCR275680 Mouse Optn ORF Clone(NM_181848.4) Inquiry
MiUTR1H-07076 OPTN miRNA 3'UTR clone Inquiry
CDFR014465 Rat Optn cDNA Clone(NM_145081.3) Inquiry
CDFH013140 Human OPTN cDNA Clone(NM_001008212.1) Inquiry
CDFH013139 Human OPTN cDNA Clone(NM_001008213.1) Inquiry
CDFH013138 Human OPTN cDNA Clone(NM_001008211.1) Inquiry
CDFG003502 Human OPTN cDNA Clone(NM_021980.4) Inquiry
MiUTR3H-04982 OPTN miRNA 3'UTR clone Inquiry
CDCS419176 Human OPTN ORF Clone (BC032762) Inquiry
CDCR381512 Rat Optn ORF Clone(NM_145081.3) Inquiry
CDCR340338 Human OPTN ORF Clone(NM_001008213.1) Inquiry
CDCR340336 Human OPTN ORF Clone(NM_001008212.1) Inquiry
CDCR340333 Human OPTN ORF Clone(NM_001008211.1) Inquiry
CDCR307336 Human OPTN ORF Clone(NM_021980.4) Inquiry
CDCB185990 Rabbit OPTN ORF clone (XM_008268095.1) Inquiry
CDCB173215 Danio rerio OPTN ORF Clone (NM_001100066) Inquiry
CDCB166227 Chicken OPTN ORF Clone (NM_204236) Inquiry
CDCS419175 Human OPTN ORF Clone (BC013876) Inquiry
CDCB159089 Human OPTN ORF clone (BC013876) Inquiry
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