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NUDT15


Official Full Name
nudix hydrolase 15
Organism
Homo sapiens
Gene ID
55270
Background
This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Apr 2016]
Synonyms
MTH2; NUDT15D

Cat.No. Product Name Price
SHH356072 shRNA set against Human NUDT15 (NM_018283.1) Inquiry
SHH356076 shRNA set against Mouse NUDT15 (NM_172527.2) Inquiry
SHH356080 shRNA set against Rat NUDT15 (NM_001106049.1) Inquiry
SHR025598 shRNA set against Mouse Nudt15(NM_172527.2) Inquiry
SHR025616 shRNA set against Human NUDT15(NM_018283.1) Inquiry
SHW006223 shRNA set against Danio rerio NUDT15 (NM_001002107) Inquiry
Cat.No. Product Name Price
CDFG001679 Human NUDT15 cDNA Clone(NM_018283.1) Inquiry
CDFR005823 Rat Nudt15 cDNA Clone(NM_001106049.1) Inquiry
MiUTR1H-06968 NUDT15 miRNA 3'UTR clone Inquiry
MiUTR1M-07877 NUDT15 miRNA 3'UTR clone Inquiry
CDCB167698 Danio rerio NUDT15 ORF Clone (NM_001002107) Inquiry
CDCB183928 Rabbit NUDT15 ORF clone (XM_002720720.2) Inquiry
CDCH392422 Mouse NUDT15 ORF clone(NM_172527.2) Inquiry
CDCL140545 Human NUDT15 ORF clone (NM_018283.1) Inquiry
CDCR372851 Rat Nudt15 ORF Clone(NM_001106049.1) Inquiry
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