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NUDT1


Official Full Name
nudix hydrolase 1
Organism
Homo sapiens
Gene ID
4521
Background
Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some of which encode distinct isoforms, have been identified. Additional variants have been observed, but their full-length natures have not been determined. A rare single-nucleotide polymorphism that results in the production of an additional, longer isoform (p26) has been described. [provided by RefSeq, Dec 2018]
Synonyms
MTH1

Cat.No. Product Name Price
SHR025680 shRNA set against Human NUDT1(NM_198949.1) Inquiry
SHR025716 shRNA set against Rat Nudt1(NM_057120.1) Inquiry
SHW018476 shRNA set against Danio rerio NUDT1 (NM_213418) Inquiry
SHH356008 shRNA set against Human NUDT1 (NM_002452.3) Inquiry
SHH356012 shRNA set against Mouse NUDT1 (NM_008637.1) Inquiry
SHH356016 shRNA set against Rat NUDT1 (NM_057120.1) Inquiry
SHR025544 shRNA set against Human NUDT1(NM_002452.3) Inquiry
SHR025634 shRNA set against Mouse Nudt1(NM_008637.1) Inquiry
SHW000253 shRNA set against Chicken NUDT1 (NM_001006160) Inquiry
Cat.No. Product Name Price
CDFG012989 Human NUDT1 cDNA Clone(NM_198948.1) Inquiry
MiUTR3H-03264 NUDT1 miRNA 3'UTR clone Inquiry
MiUTR3H-03263 NUDT1 miRNA 3'UTR clone Inquiry
MiUTR3H-03262 NUDT1 miRNA 3'UTR clone Inquiry
MiUTR3H-03260 NUDT1 miRNA 3'UTR clone Inquiry
MiUTR1R-04317 NUDT1 miRNA 3'UTR clone Inquiry
MiUTR1M-07871 NUDT1 miRNA 3'UTR clone Inquiry
MiUTR1H-06963 NUDT1 miRNA 3'UTR clone Inquiry
MiUTR1H-06962 NUDT1 miRNA 3'UTR clone Inquiry
CDFR013731 Rat Nudt1 cDNA Clone(NM_057120.1) Inquiry
CDFH012960 Human NUDT1 cDNA Clone(NM_002452.3) Inquiry
CDFG012996 Human NUDT1 cDNA Clone(NM_198954.1) Inquiry
CDFG012994 Human NUDT1 cDNA Clone(NM_198952.1) Inquiry
CDFG012992 Human NUDT1 cDNA Clone(NM_198953.1) Inquiry
CDFG012991 Human NUDT1 cDNA Clone(NM_198950.1) Inquiry
SKO1024 NUDT1 Validated sgRNA vector Inquiry
CDFG012988 Human NUDT1 cDNA Clone(NM_198949.1) Inquiry
CDCR326394 Human NUDT1 ORF Clone(NM_198948.1) Inquiry
MiUTR3H-03265 NUDT1 miRNA 3'UTR clone Inquiry
CDCS410805 Human NUDT1 ORF Clone (BC051375) Inquiry
CDCS410804 Human NUDT1 ORF Clone (BC014618) Inquiry
CDCR380764 Rat Nudt1 ORF Clone(NM_057120.1) Inquiry
CDCR326407 Human NUDT1 ORF Clone(NM_198954.1) Inquiry
CDCR326405 Human NUDT1 ORF Clone(NM_198953.1) Inquiry
CDCR326402 Human NUDT1 ORF Clone(NM_198952.1) Inquiry
CDCR326398 Human NUDT1 ORF Clone(NM_198950.1) Inquiry
CDCR326396 Human NUDT1 ORF Clone(NM_198949.1) Inquiry
CDCR283208 Human NUDT1 ORF Clone(NM_002452.3) Inquiry
CDCL140517 Human Nudt1 ORF clone (NM_008637.1) Inquiry
CDCB188806 Rabbit NUDT1 ORF clone (XM_008252638.1) Inquiry
CDCB179951 Danio rerio NUDT1 ORF Clone (NM_213418) Inquiry
CDCB161728 Chicken NUDT1 ORF Clone (NM_001006160) Inquiry
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