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NPHS1


Official Full Name
NPHS1 adhesion molecule, nephrin
Organism
Homo sapiens
Gene ID
4868
Background
This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.[provided by RefSeq, Oct 2009]
Synonyms
CNF; NPHN; nephrin

Cat.No. Product Name Price
SHR018200 shRNA set against Mouse Nphs1(NM_019459.2) Inquiry
SHH354248 shRNA set against Human NPHS1 (NM_004646.3) Inquiry
SHH354252 shRNA set against Mouse NPHS1 (NM_019459.2) Inquiry
SHH354256 shRNA set against Rat NPHS1 (NM_022628.1) Inquiry
SHR018318 shRNA set against Rat Nphs1(NM_022628.1) Inquiry
SHW009701 shRNA set against Danio rerio NPHS1 (NM_001040687) Inquiry
Cat.No. Product Name Price
CDFL008501 Mouse Nphs1 cDNA Clone(NM_019459.2) Inquiry
CDFR012059 Rat Nphs1 cDNA Clone(NM_022628.1) Inquiry
MiUTR1M-07774 NPHS1 miRNA 3'UTR clone Inquiry
MiUTR1R-04253 NPHS1 miRNA 3'UTR clone Inquiry
MiUTR3H-05263 NPHS1 miRNA 3'UTR clone Inquiry
CDCB171176 Danio rerio NPHS1 ORF Clone (NM_001040687) Inquiry
CDCB184938 Rabbit NPHS1 ORF clone (XM_002722245.2) Inquiry
CDCL139445 Human Nphs1 ORF clone (NM_019459.2) Inquiry
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