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NGLY1

Official Full Name
N-glycanase 1
Organism
Homo sapiens
GeneID
55768
Background
This gene encodes an enzyme that catalyzes hydrolysis of an N(4)-(acetyl-beta-D-glucosaminyl) asparagine residue to N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue. The encoded enzyme may play a role in the proteasome-mediated degradation of misfolded glycoproteins. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2009]
Synonyms
CDDG; PNG1; CDG1V; PNG-1; PNGase;

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