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NFKBIE

Official Full Name
NFKB inhibitor epsilon
Organism
Homo sapiens
GeneID
4794
Background
The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus. [provided by RefSeq, Sep 2011]
Synonyms
IKBE;

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