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NDUFV1


Official Full Name
NADH:ubiquinone oxidoreductase core subunit V1
Organism
Homo sapiens
Gene ID
4723
Background
The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009]
Synonyms
UQOR1; CI-51K; CI51KD; MC1DN4

Cat.No. Product Name Price
CLKO-0846 NDUFV1 KO Cell Lysate-HEK293T Inquiry
Cat.No. Product Name Price
SHH350936 shRNA set against Mouse NDUFV1 (NM_133666.2) Inquiry
SHH350940 shRNA set against Rat NDUFV1 (NM_001006972.1) Inquiry
SHR005624 shRNA set against Mouse Ndufv1(NM_133666.2) Inquiry
SHR005962 shRNA set against Rat Ndufv1(NM_001006972.1) Inquiry
SHW002166 shRNA set against Chicken NDUFV1 (NM_001031583) Inquiry
SHW006972 shRNA set against Danio rerio NDUFV1 (NM_001003747) Inquiry
Cat.No. Product Name Price
CDFR001502 Rat Ndufv1 cDNA Clone(NM_001006972.1) Inquiry
MiUTR1M-07576 NDUFV1 miRNA 3'UTR clone Inquiry
MiUTR1R-04156 NDUFV1 miRNA 3'UTR clone Inquiry
SKO0628 NDUFV1 Validated sgRNA vector Inquiry
CDCB163641 Chicken NDUFV1 ORF Clone (NM_001031583) Inquiry
CDCB168447 Danio rerio NDUFV1 ORF Clone (NM_001003747) Inquiry
CDCL137377 Mouse Ndufv1 ORF clone (NM_133666.2) Inquiry
CDCR368611 Rat Ndufv1 ORF Clone(NM_001006972.1) Inquiry
CDCS408812 Human NDUFV1 ORF Clone (BC008146) Inquiry
CDCS408813 Human NDUFV1 ORF Clone (BC015645) Inquiry
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